Sathyabama Institute of Science and Technology B.E. - Mechanical Engineering SBMA4003 Drug Delivery System Syllabus

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Sathyabama Institute of Science and Technology B.E. - Mechanical Engineering SBMA4003 Drug Delivery System Syllabus

SATHYABAMA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL OF MECHANICAL ENGINEERING

SBMA4003 DRUG DELIVERY SYSTEMS
L T P Credits Total Marks
3 0 0 3 100

UNIT 1 SUSTAINED AND CONTROLLED DRUG DELIVERY 9 Hrs.
Introduction, properties of drugs, Pharmacokinetic properties of drugs, sustained release formulations – concept, physic
chemical biological properties of drugs, advantages and disadvantages –controlled drug delivery systems–automatically
controlled drug delivery systems and their biomedical applications.

UNIT 2 POLYMERS &TARGETTED DRUG DELIVERY SYSTEMS 9 Hrs.
Polymers used in drug delivery systems – modules, classification, characterization, advantages and disadvantages of
polymer, targeted drug delivery systems–concepts–nanoparticles–liposomes, microspheres– hydrogels

UNIT 3 TRANSDERMAL DRUG DELIVERY SYSTEMS 9 Hrs.
Transdermal penetration of drugs – formulation – addition – polymers intransdermal drug delivery system– iontophoresis–
transdermal controlled release products and devices

UNIT 4 IMPLANTABLE DRUG DELIVERY SYSTEMS 9 Hrs.
Implantablemicro–pumpsystems–peristalticmicrop ump–osmoticmicropump-diaphragmmicropump– Fluorocarbon propellent
driven micro pump – solenoid driver reciprocate micro pump – programmable implanted drug administrative device(DAD)

UNIT 5 SITE SPECIFIC DRUG DELIVERY SYSTEMS 9 Hrs.
Development in insulin therapy using biomedical controlled drug delivery systems–drug delivery using mono clonal
antibodies– ole of biosensors and transducer in diagnostic
Max. 45 Hrs.

COURSE OUTCOMES
On completion of the course, student will be able to
CO1 - Understands the design of drug delivery systems for various routes of administration.
CO2 - Explains the techniques used in the development of drug delivery systems.
CO3 - Discuss the current trends in drug targeting, biotechnology products and modified release drug delivery
CO4 - Identify the technological and documented problems with the development of drug delivery systems.
CO5 - Analyze the release of various drugs using sensors and monoclonal antibodies.
CO6 - Compare the cost effective strategy for development of new dosage forms

TEXT / REFERENCE BOOKS
1. Vyas S.P. Khar RKTargetted and controlled drug delivery Novel Carrier System CBSPD, 2006.
2. Anya M Hillery et al Drug delivery and targeting CRC press, 2010
3. Robinson R Robinson Conventional drug delivery systems CRC press,2004

END SEMESTER EXAMINATION QUESTION PAPER PATTERN
Max. Marks: 100 Exam Duration: 3 Hrs.
PART A: 10 Questions of 2 marks each-No choice 20 Marks
PART B: 2 Questions from each unit of internal choice; each carrying 16 marks 80 Marks