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Sathyabama Institute of Science and Technology B.Sc - BioChemistry SBB1201 Zoology Syllabus SATHYABAMA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL OF BIO AND CHEMICAL ENGINEERING SBB1201 IMMUNOLOGY L T P Credits Total marks 4 0 0 4 100 Unit 1 HISTORY OF IMMUNOLOGY 12 Hrs.. History of Immunology – Host-parasite relationship – Immunity –Innate and acquired immunity – Humoral and Cellmediated immunity. UNIT 2 PROPERTIES OF IMMUNE CELLS 12 Hrs.. Structure, Functions and Properties of: Immune Cells – Stem cell, T cell, B cell, NK cell, Macrophage, Neutrophil, Eosinophil, Basophil, Mast cell, Dendritic cell; and Immune Organs – Bone Marrow, Thymus, Lymph Node, Spleen, GALT, MALT, CALT UNIT 3 ANTIGENS AND ANTIBODIES 12 Hrs.. Antigens – Types, properties – Immunoglobulins – Structure,types and Functions, Antigenic determinants on antibodies(Isotypic, allotypic, idiotypic); VDJ rearrangements; Complement – Classical and alternative pathways. UNIT 4 MONOCLONAL ANTIBODIES 12 Hrs.. Monoclonal antibodies, .Antigen – Antibody reactions: Agglutination – Precipitation –Complement fixation – Immunofluorescence – ELISA, RIA. UNIT 5 CELL MEDIATED IMMUNITY 12 Hrs.. Autoimmunity: Hypersensitivity reactions – Antibody mediated – Type I, Type II and Type III – cell mediated - Type IV; Transplantation immunology; Tumor immunology Max Hours.60 TEXT / REFERENCE BOOK 1. Zeev Pancer and Max D. Cooper, (2006), The Evolution of Adaptive Immunity, Ann. Rev.Immunol., 24: 497–518 2. Roitt Evan, Brostoff J. Male D. (1993) Immunology 6th Ed., Mosby & Co. London. 3. Roitt I. M. (1988) Essentials of Immunology, ELBS, London. 4. Roitt M. (1984) Essentials of Immunology, P. G. Publishers Pvt. Ltd., New Delhi. 5. Stites D. P., Stobo J. D., Fudenberg H. H. and Wells J. V., (1982), Basic and ClinicalImmunology, 4th Ed., Lange Medical Publications, Maruzen Asia Pvt. Ltd., Singapore 6. Janeway Charles A., Paul Travers, Mark Walport, Mark Shlomchik. Immunobiologyinteractive. 2005. Garland Science Publishing. USA. END SEMESTER EXAMINATION QUESTION PAPER PATTERN Max. Marks : 100 Exam Duration : 3 Hrs. PART A : 10 questions of 2 marks each - No choice 20 Marks PART B : 2 questions from each unit of internal choice; each carrying 16 marks 80 Marks |
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