Sathyabama Institute of Science and Technology B.Tech - BioTechnology SBTA1402 Immunotechnology Syllabus

[KunwarR]

Sathyabama Institute of Science and Technology B.Tech - BioTechnology SBTA1402 Immunotechnology Syllabus


SATHYABAMA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL OF BIO AND CHEMICAL ENGINEERING

SBTA1402 IMMUNOTECHNOLOGY
L T P Credits Total Marks
3 * 0 3 100

UNIT 1 INTRODUCTION TO IMMUNOLOGY AND IMMUNE SYSTEM 9 Hrs.
History and Scope of Immunology, Hematopoiesis, Innate and Acquired Immunity; Cells of the immune system, Primary and
Secondary lymphoid organs. Maturation, structure, activation and differentiation of T and B cells.

UNIT 2 HUMORAL IMMUNITY 11 Hrs.
Antigens: Characteristics and Types of Antigens, Factors affecting the immunogenicity, Haptens, Antigenic Determinants,
Adjuvants, Immunoglobulins: Basic structures, classes and sub classes; Molecular Biology of Immunoglubulin synthesis,
Antigenic determinants on Immunoglobulins. Monoclonal antibodies. Complement system - Alternate, Classical and Lectin
pathways.

UNIT 3 CELL MEDIATED IMMUNITY 7 Hrs.
Phagocytosis, Inflammatory mediators, Structure, types and function of MHC, Exogenous and Endogenous pathways of
antigen processing and presentation; Cytokines - Characteristics, function and regulation of the immune response.

UNIT 4 IMMUNOTECHNIQUES 9 Hrs.
Nature of Antigen Antibody Interactions, Precipitation reactions, Agglutination reactions - Immunofluorenscence,
Immunoelectroscopy, RIA, ELISA. Detection of bacterial endotoxins using immunological methods (LAL Test), Western Blot

UNIT 5 IMMUNOLOGICAL DISORDERS 9 Hrs.
Hyper-sensitivity, Autoimmunity, Immunological Tolerance, Immunodeficiency diseases: Primary and secondary diseases,
Transplantation immunology, Tumor immunology.
Max.45 Hrs.

COURSE OUTCOMES
On completion of course, student will able to
CO1 - Understand overall concept of immune system.
CO2 - Acquire knowledge about different cells and organs involved in immune system.
CO3 - Recognize effectors molecules fight against infectious diseases.
CO4 - Demonstrate to produce monoclonal antibodies to diagnose and treat infectious diseases.
CO5 - Apply suitable knowledge to develop acquired immunity to maintain health.
CO6 - Implement immunotechniques to diagnose infectious diseases.

TEXT / REFERENCE BOOKS
1. Rao C.V., Text Book of Immunology, 2008.
2. Sunil Kumar Mohanty, K. Sai Leela, Text Book of Immunology, 2014.
3. Richard A.Goldsby, Thomas J. Kindt, Barsara A. Osborne, Janis Kuby, Immunology, 5th Edition, WH Freeman &
Company, 1991.
4. Ivan M. Roitt, Brostoff J. and Male D., Essential Immunology, 6th Edition, Mosby Harcourt Publishers, 2001.

END SEMESTER EXAMINATION QUESTION PAPER PATTERN
Max. Marks: 100 Exam Duration: 3 Hrs.
Part A: 10 Questions of 2 marks each - No choice 20 Marks
Part B: 2 Questions from each unit of internal choice, each carrying 16 marks 80 Marks