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Sathyabama Institute of Science and Technology B.Tech - BioTechnology SCHA1511 Transport Phenomena for Bioprocess Syllabus SATHYABAMA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL OF BIO AND CHEMICAL ENGINEERING SCHA1511 TRANSPORT PHENOMENA FOR BIOPROCESSES L T P Credits Total Marks 3 * 0 3 100 UNIT 1 INTRODUCTION TO MOMENTUM TRANSPORT 9 Hrs. Fluids- Definition, Newton’s law of viscosity, Classification of fluids- Newtonian and non Newtonian, types of flow, basic equations of fluid flow-continuity and Bernoulli’s equation, Hagen-Pouseuille equation, Fluid mixing, mixing equipments, assessing effectiveness of mixing and power consumption in mixing, Rheology of fermentation broths. UNIT 2 MECHANISM OF MOMENTUM TRANSPORT 9 Hrs. Molecular momentum transport, Pressure and temperature dependency of viscosity, Molecular theory of the viscosity of gases at low density, Molecular theory of viscosity of liquids, viscosity of biological suspensions and emulsions, Convective momentum transport, Shell momentum balance and boundary conditions, Equation of Motion, Flow of a falling film, Flow through annulus. UNIT 3 THERMAL CONDUCTIVITY AND THE MECHANISM OF ENERGY TRANSPORT 9 Hrs. Fourier’s law of Heat Conduction, Molecular energy transport, Measurement of thermal conductivity, Temperature and pressure dependence of thermal conductivity, Theory of thermal conductivity of gases at low density, theory of thermal conductivity of liquids, Thermal conductivity of solids and composite solids, Shell energy balance and boundary conditions, Equation of energy, Steady state heat conduction in Flat slabs, slabs in series, cylinder, hollow cylinder, sphere. UNIT 4 DIFFUSIVITY AND THE MECHANISM OF MASS TRANSPORT 9 Hrs. Fick’s law of binary diffusion, Temperature and pressure dependence of diffusivities, Theory of diffusion in gases at low density, Theory of diffusion in binary liquids, Theory of diffusion on colloidal suspensions, Theory of diffusion in polymers, Shell mass balance and boundary conditions – Diffusion through heterogeneous and homogeneous chemical reaction, Diffusion through stagnant flim. Convective mass transport, Maxwell stefan’s equation for multicomponent diffusion in gases at low density. UNIT 5 MATHEMATICAL MODELING OF BIOLOGICAL PROCESSES 9 Hrs. Modeling cycle, System and types, Macroscopic approach, Modeling of microbiological processes, Macroscopic balance for - defined chemical compounds, intracellular compounds, Pseudo steady state approximation for intracellular compounds, Black box description of microbial growth. Electrokinetic phenomena, Pressure diffusion and ultracentrifuge, Centrifugation of proteins, Electro-osmosis, Transport across selectively permeable membrane, Transport in porous media. Max.45 Hrs. COURSE OUTCOMES On completion of course, student will able to CO1 - Understand the chemical and physical transport processes and their mechanism CO2 - Do heat, mass and momentum transfer analysis CO3 - Analyze industrial problems along with appropriate approximations and boundary conditions. CO4 - Develop steady and time dependent solutions along with their limitations CO5 - Understand the important physical phenomena from the problem statement CO6 - Develop model equations for the given system. TEXT / REFERENCE BOOKS 1. Bird R.B., Stewart W.E. and Lightfoot E.N., Transport Phenomena, 2nd Edition, J. Wiley & Sons, New York, 2002. 2. Plawsky J.L., Transport Phenomena Fundamentals, 1st Edition, Marcel-Dekker, New York, 2001. 3. Treybal R.E., Mass Transfer Operations, 3rd Edition, McGraw Hill, 2004. 4. Nigel.J.Titchener-Hooker, Bioprocess Technology: Modeling and transport phenomena, 2nd Edition, Butterworth Heinemann, 2000. END SEMESTER EXAMINATION QUESTION PAPER PATTERN Max. Marks: 100 Exam Duration: 3 Hrs. Part A: 10 Questions of 2 marks each - No choice 20 Marks Part B: 2 Questions from each unit of internal choice, each carrying 16 marks 80 Marks |
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