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| KunwarR | Sathyabama Institute of Science and Technology B.Sc - Chemistry SCY1614 Pharmaceutical Chemistry Syllabus Sathyabama Institute of Science and Technology B.Sc - Chemistry SCY1614 Pharmaceutical Chemistry Syllabus SATHYABAMA INSTITUTE OF SCIENCE AND TECHNOLOGY DEPT. OF CHEMISTRY SCY 1614 Pharmaceutical Chemistry L T P Credits Total Marks 3 1 0 4 100 UNIT 1 INTRODUCTION TO DRUGS 12 Hrs. Terminologies – Pharmacy, Pharmacology, Pharmacodynamics, Pharmacokinetics, Pharmacognosy, Antimetabolites, Mutation, Toxicology, Pharmacotherapeutics, Chemotherapy, Therapeutic index – Classification of Drugs – Biological, Chemical and Commercial classification – Prescribed and non-prescription drugs. UNIT 2 COMMON DRUGS 12 Hrs. Analgesics, antipyretic and anti-inflammatory agents – narcotic and non-narcotic drugs – morphine, source, structure – activity relationship and uses – pethadine, asprin, paracetamol, brufen UNIT 3 DRUGS OF IMPORTANCE – I 12 Hrs. Anaesthetics – Types – Local, General and Intravenous – CHCl3, Halothane, Nitrous oxide, Cocaine – Antipysochotic drugs – transquiliser – piperazine and benzamides – antidepressants – sedative and hypnotics – Barbiturates – Antiseptics and disinfectants – Difference – phenols, chloramines, crystal violet. UNIT 4 DRUGS OF IMPORTANCE – II 12 Hrs. Cancer and Antineoplastic drugs – Diabetes and hypoglycemic drugs – Insulin – Antibiotics – Classification – Structure, properties and therapeutic uses of Chloramphenicol, Penicillin, tetracyclines, Streptomycin, Erythromycin. UNIT 5 BLOOD AND HEAMOTOLOGICAL AGENTS 12 Hrs. Blood – grouping, composition, Rh factor, Blood pressure, hypertension and hypotension – Antihypertensive agents – Aldomet, reserpine – Clotting of blood – hematological agents – Antianaemic drugs – Cardiac glycosides – Digoxin – antiarrhythmic drugs – Quinidine – structure and therapeutic uses – Anagonists of Ca – Antianginal agents – nitriles – vasodilators – Sodium Nitroprusside and papaverine. COURSE OUTCOMES On successful completion of the course, student will be able to CO1:Explain the basic terminologies like pharmacology, pharmacokinetics, pharmacotherapeutics. CO2  iscuss the antipyretic, analgesic and anti-inflammatory agents.CO3 etermine the importance of anaesthetics, antiseptics and antidepressants.CO4 iscuss the importance of various cancer and antineoplastic drugs.CO5 iscuss the classification and importance of antibiotics.CO6:Construct the blood grouping and heamotological agents and also structure of quinidine. TEXT / REFERENCE BOOKS 1. J.Ghosh, A text book of Pharmaceutical Chemistry, S.Chand and Co. Ltd, 1999. 2. S.C. Rastogi, Biochemistry, Tata McGraw Hill Publishing Co., 1993 3. AshutoshKaur, Medicinal Chemistry, Wiley Eastern Limited, New Delhi, 1993. 4. O.Le Roy, Natural and synthetic organic medicinal compounds, Ealemi., 1976. 5. O. Kleiner and J. Martin, Bio-Chemistry, Prentice-Hall of India (P) Ltd, New Delhi,1974. END SEMESTER EXAM QUESTION PAPER PATTERN Max. Marks : 100 Exam Duration : 3 Hrs. PART A : 10 Questions of 2 Marks each-No choice 20 Marks PART B : 2 Questions from each unit of internal choice, each carrying 16 Marks. 80 Marks ( |
