Sathyabama Institute of Science and Technology B.Sc - Chemistry SCY1614 Pharmaceutical Chemistry Syllabus

[KunwarR]

Sathyabama Institute of Science and Technology B.Sc - Chemistry SCY1614 Pharmaceutical Chemistry Syllabus

SATHYABAMA INSTITUTE OF SCIENCE AND TECHNOLOGY DEPT. OF CHEMISTRY

SCY 1614 Pharmaceutical Chemistry
L T P Credits
Total Marks
3 1 0 4
100

UNIT 1 INTRODUCTION TO DRUGS 12 Hrs.
Terminologies – Pharmacy, Pharmacology, Pharmacodynamics, Pharmacokinetics, Pharmacognosy, Antimetabolites, Mutation, Toxicology,
Pharmacotherapeutics, Chemotherapy, Therapeutic index – Classification of Drugs – Biological, Chemical and Commercial classification – Prescribed and
non-prescription drugs.

UNIT 2 COMMON DRUGS 12 Hrs.
Analgesics, antipyretic and anti-inflammatory agents – narcotic and non-narcotic drugs – morphine, source, structure – activity relationship and uses –
pethadine, asprin, paracetamol, brufen

UNIT 3 DRUGS OF IMPORTANCE – I 12 Hrs.
Anaesthetics – Types – Local, General and Intravenous – CHCl3, Halothane, Nitrous oxide, Cocaine – Antipysochotic drugs – transquiliser – piperazine
and benzamides – antidepressants – sedative and hypnotics – Barbiturates – Antiseptics and disinfectants – Difference – phenols, chloramines, crystal
violet.

UNIT 4 DRUGS OF IMPORTANCE – II 12 Hrs.
Cancer and Antineoplastic drugs – Diabetes and hypoglycemic drugs – Insulin – Antibiotics – Classification – Structure, properties and therapeutic uses of
Chloramphenicol, Penicillin, tetracyclines, Streptomycin, Erythromycin.

UNIT 5 BLOOD AND HEAMOTOLOGICAL AGENTS 12 Hrs.
Blood – grouping, composition, Rh factor, Blood pressure, hypertension and hypotension – Antihypertensive agents – Aldomet, reserpine – Clotting of
blood – hematological agents – Antianaemic drugs – Cardiac glycosides – Digoxin – antiarrhythmic drugs – Quinidine – structure and therapeutic uses –
Anagonists of Ca – Antianginal agents – nitriles – vasodilators – Sodium Nitroprusside and papaverine.

COURSE OUTCOMES
On successful completion of the course, student will be able to
CO1:Explain the basic terminologies like pharmacology, pharmacokinetics, pharmacotherapeutics.
CO2iscuss the antipyretic, analgesic and anti-inflammatory agents.
CO3etermine the importance of anaesthetics, antiseptics and antidepressants.
CO4iscuss the importance of various cancer and antineoplastic drugs.
CO5iscuss the classification and importance of antibiotics.
CO6:Construct the blood grouping and heamotological agents and also structure of quinidine.

TEXT / REFERENCE BOOKS
1. J.Ghosh, A text book of Pharmaceutical Chemistry, S.Chand and Co. Ltd, 1999.
2. S.C. Rastogi, Biochemistry, Tata McGraw Hill Publishing Co., 1993
3. AshutoshKaur, Medicinal Chemistry, Wiley Eastern Limited, New Delhi, 1993.
4. O.Le Roy, Natural and synthetic organic medicinal compounds, Ealemi., 1976.
5. O. Kleiner and J. Martin, Bio-Chemistry, Prentice-Hall of India (P) Ltd, New Delhi,1974.

END SEMESTER EXAM QUESTION PAPER PATTERN
Max. Marks : 100 Exam Duration : 3 Hrs.
PART A : 10 Questions of 2 Marks each-No choice 20 Marks
PART B : 2 Questions from each unit of internal choice, each carrying 16 Marks. 80 Marks
(